The mechanism of polyphyllin in the treatment of gastric cancer was verified based on network pharmacology and experimental validation.

Researchers predicted targets and mechanisms of Polyphyllin for treating gastric cancer using Paris polyphylla rhizomes. Important for understanding traditional Chinese medicine and developing new GC treatments.

Lu D et al (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e31452

PubMed:

38831826

Chrysanthemum morifolium Ramat extract and probiotics combination ameliorates metabolic disorders through regulating gut microbiota and PPARα subcellular localization.

Gao X et al (2024).

Chin Med.

DOI:

10.1186/s13020-024-00950-w

PubMed:

38831430

A graminan type fructan from Achyranthes bidentata prevents the kidney injury in diabetic mice by regulating gut microbiota.

A compound from Achyranthis bidentatae (ABPW1) protects against kidney damage and intestinal issues in diabetic mice by modulating gut microbiota and producing beneficial short chain fatty acids. Potential application for diabetic kidney disease prevention.

Si H et al (2024).

Carbohydr Polym.

DOI:

10.1016/j.carbpol.2024.122275

PubMed:

38823933

Intestinal lymphatic transport of Smilax china L. pectic polysaccharide via Peyer's patches and its uptake and transport mechanisms in mononuclear phagocytes.

Liu J et al (2024).

Carbohydr Polym.

DOI:

10.1016/j.carbpol.2024.122256

PubMed:

38823922

Solanum nigrum L. berries extract ameliorated the alcoholic liver injury by regulating gut microbiota, lipid metabolism, inflammation, and oxidative stress.

Wang X et al (2024).

Food Res Int.

DOI:

10.1016/j.foodres.2024.114489

PubMed:

38823872

Decrease in GPSM2 mediated by the natural product luteolin contributes to colon adenocarcinoma treatment and increases the sensitivity to fluorouracil.

Yang C et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116847

PubMed:

38823277

Acorus tatarinowii oils exert protective effects on microglia-mediated inflammatory injury via restoring gut microbiota composition in experimental stroke rats.

Researchers studied the effects of Acorus tatarinowii oils on microglial inflammation after ischemic stroke. Results showed AT oils reduced cerebral damage, inflammation, and improved gut microbiota balance. Gut microbiota played a crucial role in the protective effects of AT oils.

Huang Y et al (2024).

Brain Res Bull.

DOI:

10.1016/j.brainresbull.2024.110990

PubMed:

38821245

Protective effects of Abrus cantoniensis Hance against liver injury through modulation of intestinal microbiota and liver metabolites.

Xu C et al (2024).

Ecotoxicol Environ Saf.

DOI:

10.1016/j.ecoenv.2024.116495

PubMed:

38820876