Chicory extract (CG) delayed weight gain, improved metabolism, reduced oxidative stress, and balanced gut microbiota in obese mice. CG may be beneficial for treating obesity and metabolic issues by targeting the gut microbiome and bile acid production.
Study uncovers therapeutic potential of gut microbiota and plant compounds for metabolic disorders. Key genes and bioactive compounds identified could lead to novel treatments for type 2 diabetes, NAFLD, obesity, and hypertension.
Polysaccharide from PLE0 leaves inhibits colon cancer metastasis by reducing cell migration and invasion, suppressing N-cadherin and vimentin expression, upregulating E-cadherin, and inhibiting MMP-2/9 through GSK3β/β-catenin and JNK signaling pathways. This research may lead to potential treatments for colon cancer.
BVR root extract from L. () showed promising chemopreventive effects against colon cancer cells, inducing programmed cell death and altering gene expression related to apoptosis. BVR also demonstrated antioxidant and anti-inflammatory properties. Consider using BVR as a comprehensive chemopreventive agent in colorectal cancer.
Yamogenin from plants has strong cytotoxic effects on gastric cancer cells, induces apoptosis via multiple pathways, and has moderate antioxidant properties. It may be a promising option for treating and preventing gastric cancers.