Genetics Studies

N6-methyladenosine modification of TSC1 mRNA contributes to macrophage polarization regulated by Coptisine in DSS-induced ulcerative colitis.

This study investigates how coptisine (COP), derived from Coptis chinensis, inhibits macrophage inflammation in ulcerative colitis (UC). COP's protective mechanism against UC in mice induced with dextran sulfate sodium (DSS) is explored.

Zhao M et al (2024).
Phytomedicine.
PubMed:
38014839

Targeted knockout of early nodulin-like 3 (MusaENODL3) gene in banana reveals its function in resistance to Xanthomonas wilt disease.

Researchers used CRISPR/Cas9 to disrupt the MusaENODL3 gene in bananas infected with Xanthomonas campestris bacteria, making the plants resistant to banana Xanthomonas wilt disease. This could help improve disease resistance in banana crops, important for tropical farmers who rely on bananas for food and income.

Ntui VO et al (2023).
Plant Biotechnol J.
PubMed:
38013635

Components study on gastroprotective effect and holistic mechanism of the herbal pair Alpinia officinarum - Cyperus rotundus based on spectrum-effect relationship and integrated transcriptome and metabolome analyses.

HPAC, an herbal pair used to treat gastric ulcers, has a proven history of success. Consider implementing it in your lab to improve treatment options for ulcers.

Qu H et al (2023).
J Ethnopharmacol.
PubMed:
38012972

Reactive oxygen species induced oxidative damage to DNA, lipids, and proteins of antibiotic-resistant bacteria by plant-based silver nanoparticles.

This study found that plant-based silver nanoparticles (AgNPs) effectively damage antibiotic-resistant bacteria through oxidative damage. AgNPs synthesized through and extracts were most effective in and , respectively. The results show that AgNPs can kill bacteria by altering DNA, lipids, and proteins.

Ali HM et al (2023).
3 Biotech.
PubMed:
38009163

Molecular mapping of two novel cold resistance genes in common wheat by 660K SNP array.

The study discovered and mapped two new cold resistance genes in wheat, which can help improve wheat yield in low temperature conditions. The genes control cold resistance and their identification lays the foundation for further research and cloning.

Lei C et al (2023).
Mol Breed.
PubMed:
38009099