Use of iRNA in the post-transcriptional gene silencing of necrosis-inducing Phytophthora protein 1(NPP1) in Phytophthora cinnamomi.

Pascoal-Ferreira P et al (2023).

Mol Biol Rep.

DOI:

10.1007/s11033-023-08562-7

PubMed:

37326749

Spatial organization and dynamics of chromosomes and microtubules during barley mitosis.

Kaduchová K et al (2023).

Plant J.

DOI:

10.1111/tpj.16355

PubMed:

37326283

Genome-wide identification and expression profiling of B3 transcription factor genes in Populus alba × Populus glandulosa.

Wei M et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1193065

PubMed:

37324718

Domestication, breeding, omics research, and important genes of Zizania latifolia and Zizania palustris.

Xie YN et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1183739

PubMed:

37324716

Re-sequencing and morphological data revealed the genetics of stone shell and kernel traits in apricot.

Zhang Q et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1196754

PubMed:

37324711

Molecular docking appraisal of Dysphania ambrosioides phytochemicals as potential inhibitor of a key triple-negative breast cancer driver gene.

Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer that lacks response to hormone therapy. There is a need for targeted molecular therapy for TNBC. The PI3K/AKT/mTOR signaling pathway plays a crucial role in TNBC, and AKT is a promising therapeutic target. In this study, researchers screened 25 compounds from a traditional herbal recipe for their anticancer properties. They found two compounds, cynaroside and epicatechin gallate, to be potent inhibitors of AKT 1 and 2 isoforms. These compounds demonstrate drug-like properties and show structural stability. Computational modeling suggests they could be effective drug candidates for TNBC, but further research is needed for clinical application.

Anifowose LO et al (2023).

In Silico Pharmacol.

DOI:

10.1007/s40203-023-00152-6

PubMed:

37323538

Pan-genome of Citrullus genus highlights the extent of presence/absence variation during domestication and selection.

Sun Y et al (2023).

BMC Genomics.

DOI:

10.1186/s12864-023-09443-w

PubMed:

37322453

HrTPS12 gene dramatically enhanced insect resistance of sea buckthorn to infection by fruit fly (Rhagoletis batava obseuriosa Kol.).

Zhao L et al (2023).

Pest Manag Sci.

DOI:

10.1002/ps.7614

PubMed:

37318769