Phytochemistry Studies

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis and autophagy.

Sophora flavescens is a traditional treatment for NSCLC, but the active compounds are not well understood. Previous research suggests that common alkaloids in the plant are only effective at high concentrations. This study aims to identify the key antitumor alkaloids in S. flavescens. This research is important as it could lead to the discovery of novel compounds for more efficient NSCLC treatment options.

Luo D et al (2023).
Phytomedicine.
PubMed:
37269775

Rapid identification of chemical compositions from three species of Siegesbeckiae Herba by ultra-performance liquid chromatography-electrospray ionization-quadrupole time of flight-mass spectrometry in combination with deoxyribonucleic acid barcoding.

Tao G et al (2023).
J Sep Sci.
PubMed:
37269050