Acorus calamus var. angustatus Besser: Insight into current research on ethnopharmacological use, phytochemistry, pharmacology, toxicology, and pharmacokinetics.
- He X et al (2023).
- Phytochemistry.
- PubMed:
- 36871902
Researchers have developed a screening system that uses dual-targeted cell membrane chromatography and liquid chromatography-mass spectroscopy to analyze receptors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This method was used to identify antiviral components in Citrus aurantium extracts, including hesperidin, neohesperidin, nobiletin, and tangeretin. In vitro experiments showed these components can inhibit virus entry into cells and interact with host-virus receptors. The study provides new insight into drug-receptor interactions and may lead to the development of new antiviral drugs.
Researchers studied the neuroprotective effects of on a mutant model of epilepsy in flies. The study showed that the extract reduced neurodegeneration, convulsions, and cognitive deficits in the flies. This was likely due to the extract's antioxidative and inhibitory properties. The findings suggest that has potential as an anticonvulsant and antiepileptogenic treatment, but more research is needed to confirm its efficacy.