Phytochemistry Studies

Comparison of Two Varieties Fig (Peggy Red and Green) Peel Extracts by Liquid Chromatography-Tandem Mass Spectrometry Analysis and for Neuroprotective Efficacy in Caenorhabditis elegans.

Researchers analyzed the ethanol extract of Peggy Red and Green fig peel through LC-MS/MS to determine its phytochemical components and neuroprotective effects. They found 50 compounds including phenols, flavonoids, and anthocyanins with antioxidant properties. Peggy Red had higher antioxidant activity and was able to reduce toxicity in Alzheimer's transgenic CL4176 by decreasing the aggregation of amyloid-beta and increasing antioxidant enzyme activities. The results suggest the potential of Peggy Red peel extract as a new drug source against AD.

Liu S, Xiao C and Wang F (2023).
J Med Food.
PubMed:
36595373