Phytochemistry Studies

Characterization and anticancer potential of Withania somnifera fruit bioactives (a native species to Pakistan) using gas chromatography-mass spectrometer, nuclear magnetic resonance and liquid chromatography-mass spectrometry-electrospray ionization.

Tabassam Q et al (2022).
J Tradit Chin Med.
PubMed:
36378048

Uncariphyllin A-J, indole alkaloids from Uncaria rhynchophylla as antagonists of dopamine D2 and Mu opioid receptors.

Researchers isolated ten new indole alkaloids from the Uncaria rhynchophylla plant, as well as eleven known analogs. These compounds were evaluated for their bioactivity on dopamine D2 and Mu opioid receptors. Two compounds showed significant antagonistic activity on both receptors, making them promising for developing natural therapeutic drugs for central nervous system diseases.

Xu Y et al (2023).
Bioorg Chem.
PubMed:
36375349