δ(18)O compound-specific stable isotope assessment: An advanced analytical strategy for sophisticated adulterations detection in essential oils - Application to spearmint, cinnamon, and bitter almond essential oils authentication.

Cuchet A et al (2023).

Talanta.

DOI:

10.1016/j.talanta.2022.123801

PubMed:

35969926

Structural Revision of the Stemona Alkaloids Tuberostemonine O, Dehydrocroomines A and B, and Dehydrocroomine.

Jiang JM et al (2022).

J Nat Prod.

DOI:

10.1021/acs.jnatprod.2c00332

PubMed:

35969376

Phenolic compounds of Zanthoxylum armatum DC as potential inhibitors of urease and SARS-CoV2 using molecular docking approach and with simulation study.

Researchers evaluated the anti-urease effects of compounds found in the leaves of Datura ceratocaula. Three phenolic compounds were identified and found to interact significantly with both urease and SARS-CoV2 vital proteins. Chlorogenic acid was the most effective in interacting with both urease and the coronavirus main protease, while gallic acid was effective in interacting with five spike proteins of SARS-CoV2. The compounds also passed several tests for drug-likeness and could potentially be used as antagonists of urease.

Chelleng N et al (2023).

Nat Prod Res.

DOI:

10.1080/14786419.2022.2110096

PubMed:

35968637

Glycoside oleandrin downregulates toll-like receptor pathway genes and associated miRNAs in human melanoma cells.

Eroğlu Güneş C et al (2022).

Gene.

DOI:

10.1016/j.gene.2022.146805

PubMed:

35964872

Nanoemulsion and nanogel containing Artemisia dracunculus essential oil; larvicidal effect and antibacterial activity.

Osanloo M et al (2022).

BMC Res Notes.

DOI:

10.1186/s13104-022-06135-8

PubMed:

35962444

Stereochemical insights into neuroprotective alkaloids from the aerial parts of Emilia sonchifolia.

Researchers isolated three alkaloids from Emilia sonchifolia plant, including a new compound called emililactam A. They separated two known compounds into their respective enantiomers, and their structures were confirmed using spectroscopic analysis and electronic circular dichroism calculations. In a cell culture study, emililactam A and two other compounds showed moderate neuroprotective effects against corticosterone-induced damage to PC12 cells.

Huang MJ et al (2022).

Fitoterapia.

DOI:

10.1016/j.fitote.2022.105267

PubMed:

35961597

Mussaendoside O, a N-triterpene cycloartane saponin, attenuates RANKL-induced osteoclastogenesis and inhibits lipopolysaccharide-induced bone loss.

Gal M et al (2022).

Phytomedicine.

DOI:

10.1016/j.phymed.2022.154378

PubMed:

35961265

Spicatulides A-G, Phenolic-Monoterpenoid Hybrids from Chloranthus spicatus.

Zhou JS et al (2022).

J Nat Prod.

DOI:

10.1021/acs.jnatprod.2c00546

PubMed:

35957573