GeoBotanical: Phytochemistry Studies

4017.

Antiurolithic efficacy of a phenolic rich ethyl acetate fraction of the aerial parts of Aerva lanata (Linn) Juss. ex Schult. in ethylene glycol induced urolithic rats.

Phytochemistry Aerva lanata

Mandal B et al (2021).; J Pharm Pharmacol.
DOI:: 10.1093/jpp/rgaa071
PubMed:: 33793840

4018.

Targeted LC-MS/MS combined with multilocus DNA metabarcoding as a combinatory approach to determine the amount and the source of pyrrolizidine alkaloids contamination in popular cooking herbs, seeds, spices and leafy vegetables.

Genetics Phytochemistry Senecio vulgaris

Picron JF et al (2021).; Food Addit Contam Part A Chem Anal Control Expo Risk Assess.
DOI:: 10.1080/19440049.2021.1889043
PubMed:: 33780325

4019.

Chemometric optimisation of pressurised liquid extraction for the determination of alliin and S-allyl-cysteine in giant garlic (Allium ampeloprasum L.) by liquid chromatography tandem mass spectrometry.

Phytochemistry Allium ampeloprasum

Peterssen-Fonseca D et al (2021).; Phytochem Anal.
DOI:: 10.1002/pca.3046
PubMed:: 33779027

4020.

Chemotaxonomic investigation of Apocynaceae for retronecine-type pyrrolizidine alkaloids using HPLC-MS/MS.

Phytochemistry Wrightia tinctoria

Barny LA et al (2021).; Phytochemistry.
DOI:: 10.1016/j.phytochem.2021.112662
PubMed:: 33774572

4021.

Analysis of pyrrolizidine alkaloids in Eupatorium fortunei Turcz. and their in vitro neurotoxicity.

Researchers analyzed the levels of pyrrolizidine alkaloids (PAs) in Eupatorium fortunei herbs and products derived from them. They found that the total PA amounts varied widely, with some exceeding the recommended intake limit. The study also showed that some PAs were neurotoxic to neural progenitor cells (NPCs) in vitro. Specifically, intermedine, intermedine N-oxide, and lycopsamine N-oxide decreased cell viability at 30 μM, and intermedine N-oxide inhibited oligodendrogenesis of NPCs at 10 μM. While short-term intake seemed unlikely to lead to acute toxic effects, chronic use warranted caution. These findings highlight the need for safe monitoring of herbs and herbal products containing PAs.

Neuroscience Phytochemistry Eupatorium fortunei

Zhang Y et al (2021).; Food Chem Toxicol.
DOI:: 10.1016/j.fct.2021.112151
PubMed:: 33774095

4022.

A review on phytochemical and therapeutic potential of Iris germanica.

Phytochemistry Iris germanica

Yousefsani BS et al (2021).; J Pharm Pharmacol.
DOI:: 10.1093/jpp/rgab008
PubMed:: 33772287

4023.

Antimicrobial activities evaluation and phytochemical screening of some selected medicinal plants: A possible alternative in the treatment of multidrug-resistant microbes.

Antimicrobial Genetics Phytochemistry Discopodium penninervium Rumex abyssinicus

Kebede T, Gadisa E and Tufa A (2021).; PLoS One.
DOI:: 10.1371/journal.pone.0249253
PubMed:: 33770121

4024.

Guaianolide sesquiterpene lactones from Achillea millefolium L.

Phytochemistry Achillea millefolium

Li H et al (2021).; Phytochemistry.
DOI:: 10.1016/j.phytochem.2021.112733
PubMed:: 33761376