Phytochemistry Studies

Simultaneous Quantification of Pharmacologically Active Alkaloid Metabolites Colchicine and Gloriosine in Gloriosa Superba L. collected from Western Ghats (India) and Adjoining Areas for the Identification of Elite Chemotype(s).

Misra A et al (2021).
J AOAC Int.
PubMed:
33484241

Application of HPLC-DAD for In Vitro Investigation of Acetylcholinesterase Inhibition Activity of Selected Isoquinoline Alkaloids from Sanguinaria canadensis Extracts.

This study explored the potential of certain plant extracts to inhibit acetylcholinesterase, an enzyme linked to neurodegenerative disorders. The extracts were obtained from plants collected before, during and after flowering, and were analyzed using a high performance liquid chromatography method. The results showed that most alkaloids in the extracts exhibited very high acetylcholinesterase activity inhibition, with IC values ranging from 0.36 to 89.14 µg/mL. The study suggests that these plant extracts have potential for further investigation as a treatment for neurodegenerative disorders such as Alzheimer's disease.

Tuzimski T and Petruczynik A (2021).
Molecules.
PubMed:
33466254