Flavonoids isolated from Rumex aquaticus exhibit neuroprotective and neurorestorative properties by enhancing neurite outgrowth and synaptophysin.

Researchers have isolated two flavonoids from the Rumex aquaticus plant, quercetin-3-O-galactoside and quercetin-3-O-arabinoside, which show promise in protecting brain cells from damage caused by ischemic stroke. The study used a rat cell line and found that the flavonoids significantly improved cell survival and neurite outgrowth in a model of ischemia. Additionally, one of the flavonoids was found to enhance the expression of synaptophysin, a marker of synapses and synaptic plasticity. These results suggest that the flavonoids could be useful in promoting stroke recovery by protecting and promoting the growth of brain cells.

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CNS Neurol Disord Drug Targets.

PubMed:

25345505

Unravelling the Triterpenoid Saponin Biosynthesis of the African Shrub Maesa lanceolata.

Moses T et al (2014).

Mol Plant.

PubMed:

25296856

Foliar treatments with Gaultheria procumbens essential oil induce defense responses and resistance against a fungal pathogen in Arabidopsis.

Vergnes S et al (2014).

Front Plant Sci.

DOI:

10.3389/fpls.2014.00477

PubMed:

25295045

Cuscuta chinensis Lam.: A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine.

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J Ethnopharmacol.

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10.1016/j.jep.2014.09.032

PubMed:

25281912

Pallidifloside D, a saponin glycoside constituent from Smilax riparia, resist to hyperuricemia based on URAT1 and GLUT9 in hyperuricemic mice.

Wu XH et al (2014).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2014.09.034

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25267580

Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs.

Boukhatem MN et al (2014).

Libyan J Med.

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10.3402/ljm.v9.25431

PubMed:

25242268

Multidrug resistance-selective antiproliferative activity of Piper amide alkaloids and synthetic analogues.

Wang YH et al (2014).

Bioorg Med Chem Lett.

DOI:

10.1016/j.bmcl.2014.08.063

PubMed:

25241925

Total Phenolic Contents and Antioxidant Activities of Different Extracts and Fractions from the Aerial Parts of Artemisia biennis Willd.

Hatami T et al (2014).

Iran J Pharm Res.

PubMed:

25237350