Phytochemistry Studies

Sesquiterpene lactones from Lactuca canadensis and their chemotaxonomic significance.

Researchers isolated 19 sesquiterpene lactones from the roots of Lactuca canadensis L. Ten of the 19 were newly discovered, including three pairs of zaluzanin C-type guaianolides and six eudesmanolides. 1D and 2D NMR and high resolution mass spectroscopy were used to identify the new compounds as 3-epizaluzanin C-3-O-β-glucopyranoside and 11,13-dehydrolactuside C. The sesquiterpene lactone profile of the species is dominated by zaluzanin C-type guaianolides and eudesmanolides. The differences in this profile compared to other taxa in the genus are discussed.

Michalska K, Szneler E and Kisiel W (2013).
Phytochemistry.
PubMed:
23522933

Structure and absolute configuration of methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate, a sesterterpene derivative from the roots of Aletris farinosa.

Challinor VL et al (2013).
J Nat Prod.
PubMed:
23514637