A new anticholinergic steroidal alkaloid from Fritillaria imperialis of Turkish origin.
- Atta-ur-Rahman et al (1994).
- Planta Med.
- PubMed:
- 7938275
Researchers investigated the affinity of 14 quinolizidine alkaloids for nicotinic and/or muscarinic acetylcholine receptors. They found that N-methylcytisine and cytisine had the highest affinity at the nicotinic receptor, while certain types of quinolizidine alkaloids were particularly active at the muscarinic receptor. This study suggests that these compounds could potentially be used to develop drugs targeting these receptors.