Alternative Splicing of NAC Transcription Factor Gene CmNST1 Is Associated with Naked Seed Mutation in Pumpkin, Cucurbita moschata.
- Shen Q and Weng Y (2023).
- Genes (Basel).
- PubMed:
- 37239322
This study screened essential oils for their potential as rapid-acting antidepressants. PC12 and BV2 cells were tested, and effective oils were given to mice, which were then subjected to behavioral tests. In vivo experiments showed that six essential oils decreased immobility time in the tail suspension test, with two oils increasing time and entries into the open arms of the elevated plus maze. Four compounds had a strong affinity for glutamate receptor subunits and are predicted to underlie the fast-acting effect. These oils and compounds are promising candidates for further study as fast-acting antidepressants.
A new dietary supplement, PFPE-CH, made from a mixture of cold-pressed coconut oil and honey, has shown promising results in reducing the risk of tumor formation and minimizing the side effects of chemotherapeutic drugs in breast cancer treatment. The toxicity study revealed no harmful effects at a high dosage, and long-term use did not impact kidney or liver function. In a cancer prevention study, PFPE-CH significantly decreased tumor incidence by up to 71.4% without adverse effects. Furthermore, PFPE-CH enhanced the effectiveness of chemotherapy while reducing its toxicity. These findings suggest that PFPE-CH is a safe and effective option for breast cancer treatment.