Standardized Centella asiatica (ECa 233) extract decreased pain hypersensitivity development in a male mouse model of chronic inflammatory temporomandibular disorder.
The study found that ECa 233, a Centella asiatica extract, reduces inflammation and pain in mice with temporomandibular disorder (TMD). It may be a safe alternative treatment with maximum effectiveness at a dosage of 100 mg/kg.
- Nattapon R et al (2023).
- Sci Rep.
- PubMed:
- 37095163