Add-On Treatment with Passiflora incarnata L., herba, during Benzodiazepine Tapering in Patients with Depression and Anxiety: A Real-World Study.

The study tested the effectiveness of a natural extract in reducing benzodiazepine misuse in depressed and anxious patients long-term treated with benzodiazepines. The study involved 186 patients, with half receiving the extract as an add-on treatment. The results showed a significantly higher rate of reduction in benzodiazepine dosage in the group receiving the extract, with complete discontinuation achieved at 1 and 3 months. This suggests the extract may be an effective add-on treatment during benzodiazepine tapering. Further studies are needed to investigate its potential in managing this important health issue.

Zanardi R et al (2023).

Pharmaceuticals (Basel).

DOI:

10.3390/ph16030426

PubMed:

36986524

Phytochemical Profile, Antioxidant, Antimicrobial and Cytoprotective Effects of Cornelian Cherry (Cornus mas L.) Fruit Extracts.

Aurori M et al (2023).

Pharmaceuticals (Basel).

DOI:

10.3390/ph16030420

PubMed:

36986519

Characterization of Lemon Pepper and Black Ginger Extracts and Macroemulsions as Natural Pain Relievers for Spice Stick Balsam Formulation.

Yanti, Harijono C and Lay BW (2023).

Pharmaceuticals (Basel).

DOI:

10.3390/ph16030371

PubMed:

36986474

New Approaches on the Anti-Inflammatory and Cardioprotective Properties of Taraxacum officinale Tincture.

Epure A et al (2023).

Pharmaceuticals (Basel).

DOI:

10.3390/ph16030358

PubMed:

36986458

Rosmarinus officinalis and Mentha piperita Oils Supplementation Enhances Memory in a Rat Model of Scopolamine-Induced Alzheimer's Disease-like Condition.

Peppermint and rosemary oils were shown to have nootropic and anti-amnesic effects in rats with scopolamine-induced amnesia-like Alzheimer's disease (AD). The oils were orally administered to rats, and in the nootropic phase, both oils showed a decrease in latency times and memory errors. In the therapeutic phase, the oils enhanced memory processing. The hippocampus exhibited elevated BDNF levels, and immunohistochemistry findings showed increased hippocampal neurogenesis. Gas chromatography-mass spectrometry analysis of the oils revealed compounds with potential efficacy in memory and cognition. The combination of the two oils produced more anti-amnesic activity and had possible therapeutic activity for memory enhancement in AD patients.

Al-Tawarah NM et al (2023).

Nutrients.

DOI:

10.3390/nu15061547

PubMed:

36986277

Repeated 28-Day Oral Toxicological Study and Gastroprotective Effects of Nigella sativa L. Oil (Shuhada) against Ethanol-Induced Gastric Mucosal Injury in Rats.

Sanpinit S et al (2023).

Nutrients.

DOI:

10.3390/nu15061532

PubMed:

36986262

Ellagitannins from Castanea sativa Mill. Leaf Extracts Impair H. pylori Viability and Infection-Induced Inflammation in Human Gastric Epithelial Cells.

Piazza S et al (2023).

Nutrients.

DOI:

10.3390/nu15061504

PubMed:

36986236

Leaf Extract of Perilla frutescens (L.) Britt Promotes Adipocyte Browning via the p38 MAPK Pathway and PI3K-AKT Pathway.

Chen F et al (2023).

Nutrients.

DOI:

10.3390/nu15061487

PubMed:

36986217