All Studies

The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind randomized controlled trial.

In a randomized, double-blind, placebo-controlled trial, ginger supplementation significantly reduced disability, physical and psychological quality of life, neurofilament light chain, interleukin-17, and neutrophil to lymphocyte ratio in patients with relapsing-remitting multiple sclerosis (MS), but did not affect body mass index or matrix metalloproteinase-9 levels. These findings suggest that ginger may be a promising adjuvant therapy for MS.

Foshati S et al (2023).
Food Funct.
PubMed:
36974730

Preclinical Evidence-based Neuroprotective Potential of Silibinin.

Silibinin, a natural product found in Silybum marianum, has been used for liver diseases and shows neuroprotective activities in animal studies. Studies suggest it alters several cellular and molecular signaling pathways, including BDNF and mTOR, exhibiting antioxidant effects. This review summarizes the pharmacology, side effects, and potential therapeutic effects of silibinin for neurodegenerative disorders. Silibinin may serve as a therapeutic alternative for neurodegenerative disorders and requires further preclinical and clinical research.

Kumar Singh N and Bhushan B (2023).
Curr Drug Res Rev.
PubMed:
36974407