A New Potential Resource in the Fight against Candida auris: the Cinnamomum zeylanicum Essential Oil in Synergy with Antifungal Drug.
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- Microbiol Spectr.
- PubMed:
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In a randomized, double-blind, placebo-controlled trial, ginger supplementation significantly reduced disability, physical and psychological quality of life, neurofilament light chain, interleukin-17, and neutrophil to lymphocyte ratio in patients with relapsing-remitting multiple sclerosis (MS), but did not affect body mass index or matrix metalloproteinase-9 levels. These findings suggest that ginger may be a promising adjuvant therapy for MS.
Silibinin, a natural product found in Silybum marianum, has been used for liver diseases and shows neuroprotective activities in animal studies. Studies suggest it alters several cellular and molecular signaling pathways, including BDNF and mTOR, exhibiting antioxidant effects. This review summarizes the pharmacology, side effects, and potential therapeutic effects of silibinin for neurodegenerative disorders. Silibinin may serve as a therapeutic alternative for neurodegenerative disorders and requires further preclinical and clinical research.