Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.
- Jung MA et al (2023).
- Biomed Pharmacother.
- PubMed:
- 36921533
Researchers investigated the cognitive benefits of Ginkgo biloba extract (GBE) supplemented with sesame seed and turmeric (GBE/MST) in healthy adults. Results showed that GBE/MST improved cognitive function more significantly than GBE alone, possibly due to increased terpene lactone concentrations in the brain. These findings suggest that GBE/MST could be a promising natural intervention for cognitive enhancement in healthy adults.
A new herbal formulation called Sailuotong (SLT) consisting of extracts from Panax ginseng, Ginkgo biloba, and Crocus sativus was developed and found to enhance cognition in patients with vascular dementia (VaD) in early clinical trials. A phase III clinical trial has been developed to confirm the efficacy and safety of SLT in 238 patients with mild to moderate VaD or VaD mixed with Alzheimer’s disease. Participants will be randomly allocated to receive SLT or placebo capsules for 52 weeks, and primary outcome measures include cognitive and functional assessments. The study aims to provide important data on this novel treatment approach to VaD.
Researchers studied the effects of Rhynchophylline (RIN), a compound with anti-inflammatory and neuroprotective properties, on a mouse model of Parkinson's disease (PD). They used a combination of tests and assays to determine that RIN improved behavior, reduced neuron loss, and regulated metabolic disorders in the mice. The study showed that RIN has potential as a therapeutic agent for PD by reducing inflammation, maintaining metabolic balance, and suppressing certain proteins in the brain.