Biosynthesized selenium nanoparticles to rescue coccidiosis-mediated oxidative stress, apoptosis and inflammation in the jejunum of mice.

Abdel-Gaber R et al (2023).

Front Immunol.

DOI:

10.3389/fimmu.2023.1139899

PubMed:

36875142

Effect of Mucuna pruriens on brain NMDA receptor and tau protein gene expression in cerebral ischemic rats.

Researchers investigated the effects of pre-treatment with a seed extract and its bioactive molecule on gene expression in a rat model of cerebral ischemia (reduced blood flow to the brain). Rats were divided into four groups, with those treated with the extract or molecule showing lower neurological deficits and reduced brain damage compared to those in the control group. The study suggests that pre-treatment with the molecule and extract may reduce the negative effects of cerebral ischemia.

Parvatikar PP et al (2023).

Front Physiol.

DOI:

10.3389/fphys.2023.1092032

PubMed:

36875022

Investigation on the Mechanisms of Zanthoxylum bungeanum for Treating Diabetes Mellitus Based on Network Pharmacology, Molecular Docking, and Experiment Verification.

Huang Y et al (2023).

Biomed Res Int.

DOI:

10.1155/2023/9298728

PubMed:

36874926

Insight into the bZIP gene family in Lagenaria siceraria: Genome and transcriptome analysis to understand gene diversification in Cucurbitaceae and the roles of LsbZIP gene expression and function under cold stress.

Wang J et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2022.1128007

PubMed:

36874919

The genome sequence of the European crab apple, Malus sylvestris  (L.) Mill., 1768.

Ruhsam M et al (2022).

Wellcome Open Res.

DOI:

10.12688/wellcomeopenres.18645.1

PubMed:

36874569

Protective effect of compatible herbs in Jin-Gu-Lian formula against Alangium chinense-induced neurotoxicity via oxidative stress, neurotransmitter metabolisms, and pharmacokinetics.

The herb Aconitum carmichaelii is used in Miao medicine to treat rheumatic diseases, but its neurotoxicity poses clinical challenges. This study investigates the use of compatible herbs in Jin-Gu-Lian formula to detoxify Aconitum carmichaelii and the mechanism behind it. Rats were administered Aconitum carmichaelii extract alone or with compatible herbs, showing that the combination ameliorated oxidative damage, prevented abnormality of neurotransmitters and modulated pharmacokinetics. The study suggests that the use of compatible herbs can alleviate the neurotoxicity of Aconitum carmichaelii in traditional medicine.

Lian D et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1133982

PubMed:

36874008

Molecular mechanism of Cuscutae semen-radix rehmanniae praeparata in relieving reproductive injury of male rats induced with tripterygium wilfordii multiglycosides: A tandem mass tag-based proteomics analysis.

Han S et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1050907

PubMed:

36874004

Pharmacokinetics and tissue distribution of Ramulus Mori (Sangzhi) alkaloids in rats and its effects on liver enzyme activity.

Liu Z et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1136772

PubMed:

36873997