GeoBotanical: All Studies

10193.

Thymol improves autism-like behaviour in VPA-induced ASD rats through the Pin1/p38 MAPK pathway.

Researchers investigated the effects of thymol on autism-like behaviors in rats and related molecular mechanisms. VPA-exposed rats showed increased inflammation in the brain and decreased levels of proteins associated with neuronal function. Thymol treatment improved autism-like behaviors and rescued altered levels of inflammatory proteins and neuronal function-related proteins. Thymol achieved its effect by reducing inflammation through regulating Pin1/p38 MAPK and promoting neurodevelopment. These results suggest the potential of thymol as a therapeutic avenue for autism.

Neuroscience Thymus vulgaris

Xiong Y et al (2023).; Int Immunopharmacol.
DOI:: 10.1016/j.intimp.2023.109885
PubMed:: 36842231

10194.

Neuroprotective effects of bornyl acetate on experimental autoimmune encephalomyelitis via anti-inflammatory effects and maintaining blood-brain-barrier integrity.

Researchers investigated the immunomodulatory effects of BA on human peripheral blood mononuclear cells (PBMCs). They found that BA decreased the secretion of pro-inflammatory cytokines from PBMCs and decreased the proliferation of T cells. These findings suggest that BA may have potential therapeutic effects on autoimmune diseases. However, further studies are needed to fully explore the mechanisms and efficacy of BA in treating these diseases.

Immunology Neuroscience Pinus

Lee JI et al (2023).; Phytomedicine.
DOI:: 10.1016/j.phymed.2022.154569
PubMed:: 36842217

10195.

Comment on the "Response surface methodology optimization and HPLC-ESI-QTOF-MS/MS analysis on ultrasonic-assisted extraction of phenolic compounds from okra (Abelmoschus esculentus) and their antioxidant activity".

Phytochemistry Abelmoschus esculentus

Stężycka O and Frańska M (2023).; Food Chem.
DOI:: 10.1016/j.foodchem.2023.135729
PubMed:: 36842204

10196.

A comparative study on DNA and protein binding properties of thymol and thymoquinone.

Genetics Thymus vulgaris

Parvin SI et al (2023).; J Biomol Struct Dyn.
DOI:: 10.1080/07391102.2023.2180665
PubMed:: 36841618

10197.

Glucomannan from Aloe vera gel maintains intestinal barrier integrity via mitigating anoikis mediated by Nrf2-mitochondria axis.

Gastroenterology Aloe vera

Zhang D et al (2023).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2023.123803
PubMed:: 36841393

10198.

Structural characterization and immunomodulatory activity of an arabinogalactan from Jasminum sambac (L.) Aiton tea processing waste.

Immunology Jasminum sambac

Huang H et al (2023).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2023.123816
PubMed:: 36841385

10199.

Transcriptome analysis of gall oak (Quercus infectoria): De novo assembly, functional annotation and metabolic pathways analysis.

Genetics Quercus infectoria

Joudaki F et al (2023).; Genomics.
DOI:: 10.1016/j.ygeno.2023.110588
PubMed:: 36841311

10200.

Antidiabetic properties of mango in animal models and humans: A systematic review.

Diabetes Mangifera indica

Zarasvand SA et al (2023).; Nutr Res.
DOI:: 10.1016/j.nutres.2023.01.003
PubMed:: 36841190