All Studies

Brain Targeting by Intranasal Drug Delivery: Effect of Different Formulations of the Biflavone "Cupressuflavone" from Juniperus sabina L. on the Motor Activity of Rats.

The aerial parts of a plant species contain bioflavonoids, including cupressuflavone (CPF), a biflavonoid with various biological activities. To improve the bioavailability of CPF, three self-emulsifying drug delivery systems (SEDDS) were prepared and administered via the intranasal route to rats. Formulations B and C decreased the locomotor activity and balance of rats, with formula C at an intranasal dose of 5 mg/kg having the strongest effect. This study suggests that nose-to-brain drug delivery may be an effective method for treating neurological disorders.

Khafagy ES et al (2023).
Molecules.
PubMed:
36771021

Biosynthesized Silver Nanoparticles Using Morus alba (White Mulberry) Leaf Extract as Potential Antibacterial and Anticancer Agents.

Kumkoon T, Srisaisap M and Boonserm P (2023).
Molecules.
PubMed:
36770881

In Silico Study on the Interactions, Molecular Docking, Dynamics and Simulation of Potential Compounds from Withania somnifera (L.) Dunal Root against Cancer by Targeting KAT6A.

Deshpande SH et al (2023).
Molecules.
PubMed:
36770785