Transcriptomic Analysis of Flowering Time Genes in Cultivated Chickpea and Wild Cicer.

Gretsova M et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032692

PubMed:

36769014

Synthesis of Antimicrobial Chitosan-Silver Nanoparticles Mediated by Reusable Chitosan Fungal Beads.

Hermosilla E et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032318

PubMed:

36768640

Genome-Wide Identification of BES1 Gene Family in Six Cucurbitaceae Species and Its Expression Analysis in Cucurbita moschata.

Xu M et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032287

PubMed:

36768611

Identification and Functional Prediction of CircRNAs in Leaves of F1 Hybrid Poplars with Different Growth Potential and Their Parents.

Zhang W et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032284

PubMed:

36768607

Combination of Radix Astragali and Safflower Promotes Angiogenesis in Rats with Ischemic Stroke via Silencing PTGS2.

Radix astragali-safflower (AS) has been used for centuries in China to treat patients with ischemic stroke (IS). In this study, network pharmacology was used to uncover the mechanism of AS in treating IS. AS was shown to promote angiogenesis, which was associated with PTGS2 silence. Middle cerebral artery occlusion/reperfusion (MCAO/R) model rats were then treated with AS and showed improved cerebral infarct volume, neurological and histopathological damage, inhibition of cell apoptosis, and increased levels of PDGF-BB, EPO, and TGF-β1. AS was found to promote angiogenesis in MCAO/R rats by reversing the down-regulation of VEGF and promoting the expression of CD31. The protective mechanism of AS for IS involves PTGS2 silence.

Xu S et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032126

PubMed:

36768450

Inhibition Effect of Adipogenesis and Lipogenesis via Activation of AMPK in Preadipocytes Treated with Canavalia gladiata Extract.

Hong JW et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032108

PubMed:

36768430

Oleracone F Alleviates Cognitive Impairment and Neuropathology in APPswe/PSEN1dE9 Mice by Reducing the Expression of Vascular Cell Adhesion Molecule and Leukocyte Adhesion to Brain Vascular Endothelial Cells.

Researchers investigated the effects of flavonoids extracted from a plant on cognition of mice with Alzheimer's disease (AD) and found that treatment significantly improved memory dysfunction, decreased amyloid plaques and APP protein levels, and alleviated inflammation in the brain. In vitro studies also showed that the flavonoids blocked increases in VCAM-1 protein, reducing leukocyte infiltration to the brain and modulating brain inflammation. These findings suggest that flavonoids may have therapeutic potential for AD.

Kwon YS et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24032056

PubMed:

36768379

Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes-An In Vitro Study.

Jurič A et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms24031903

PubMed:

36768223