All Studies

N-methyl-D-aspartic acid receptor 2A functionalized stationary phase: A reliable method for pursuing potential ligands against Alzheimer's disease from natural products.

This study looked at developing a new way to identify drugs that target a specific receptor involved in Alzheimer's disease. The receptor, called NMDA-2A, plays a role in brain development. The researchers wanted to find natural products that could selectively interact with this receptor, hopefully leading to new drugs for Alzheimer's disease. Their approach could help identify potential treatments that are more precise and effective.

Chen YY et al (2023).
CNS Neurosci Ther.
PubMed:
36708133

Synthesis of a new sulfadimidine Schiff base and their nano complexes as potential anti-COVID-19 and anti-cancer activity.

Researchers synthesized a novel ligand and used it to create nanocomplexes with chromium and copper in an environmentally friendly manner. They analyzed the structure and properties of the complexes using various techniques and found them to be more stable than the free ligand. The chromium nanocomplex showed strong antitumor activity after being heated, while the copper nanocomplex exhibited good DNA cleavage. Molecular docking was used to study the potential of the complexes to bind to liver cancer and COVID-19 proteins.

Hosny S, Ragab MS and Abd El-Baki RF (2023).
Sci Rep.
PubMed:
36707628