All Studies

Effect of Enriching Gingerbread Cookies with Elder (Sambucus nigra L.) Products on Their Phenolic Composition, Antioxidant and Anti-Glycation Properties, and Sensory Acceptance.

Topka P et al (2023).
Int J Mol Sci.
PubMed:
36675004

Genome-Wide Comparative Analysis of the Fasciclin-like Arabinogalactan Proteins (FLAs) in Salicacea and Identification of Secondary Tissue Development-Related Genes.

Zhang Y et al (2023).
Int J Mol Sci.
PubMed:
36675002

Presenilin 1 Modulates Acetylcholinesterase Trafficking and Maturation.

Researchers studied the glycosylation patterns of acetylcholinesterase (AChE) in Alzheimer's disease (AD). They found that active and inactive forms of AChE have different glycosylation patterns, and that sAD patients have reduced binding to terminal mannoses compared to non-demented controls, while fAD patients that carry PSEN1 mutations have higher binding. The study also found that PS1 modulates trafficking and maturation of AChE in Golgi regions favoring the presence of active forms in the membrane. These findings provide insight into the role of AChE glycosylation in AD and its potential as a therapeutic target.

Cortés-Gómez MÁ et al (2023).
Int J Mol Sci.
PubMed:
36674948

Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.

Cardile A et al (2023).
Int J Mol Sci.
PubMed:
36674794