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Carob Seed Peels Effect on Cognitive Impairment and Oxidative Stress Status in Methionine-Induced Mice Models of Schizophrenia.

Carob seed peels (CSP) were orally administered to mice to evaluate their impact on the negative symptoms of schizophrenia. Behavioral tests were performed, and oxidative stress levels were evaluated by analyzing antioxidant enzyme levels. Both extracts showed remarkable antioxidant activity and proved to enhance cognitive impairment in animal models of schizophrenia while confirming the correlation between oxidative stress and psychiatric disorders. The study highlights the use of natural antioxidants in the improvement of cognitive impairment in schizophrenia.

Lakkab I et al (2022).
Brain Sci.
PubMed:
36552121