In vitro antioxidant analysis of flavonoids extracted from Artemisia argyi stem and their anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 macrophages.
- Wang Z et al (2023).
- Food Chem.
- PubMed:
- 36527947
Researchers evaluated the potential neuroprotective effects of rosmarinic acid (RA) in a murine model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). RA was found to prevent hyperlocomotion behavior in MPTP-treated animals and improve the monoaminergic system in healthy animals. RA also increased dopaminergic signaling in the parkinsonian mice, indicating potential neuroprotective properties for RA in preventing behavioral features observed in PD and improving neurotransmission in the healthy brain.