Protective effects of leonurine hydrochloride on pyroptosis in premature ovarian insufficiency via regulating NLRP3/GSDMD pathway.

Chi YN et al (2023).

Int Immunopharmacol.

DOI:

10.1016/j.intimp.2022.109520

PubMed:

36513022

Raw Lacquer Extract from Toxicodendron vernicifluum in Combination with ONC201 Enhances the Inhibitory Effects on Colorectal Cancer Cell Activity.

Jin Z and Jin Y (2023).

Turk J Gastroenterol.

DOI:

10.5152/tjg.2022.22048

PubMed:

36511604

Okanin from Coreopsis tinctoria Nutt. alleviates cognitive impairment in bilateral common carotid artery occlusion mice by regulating the miR-7/NLRP3 axis in microglia.

Researchers investigated the effects of okanin, the main active ingredient in Nutt. flower, on cognitive impairment following stroke. They found that okanin was able to improve cognitive impairment, inhibit microglial activation, decrease inflammasome activation, and increase miR-7 expression. Okanin was also able to suppress NLRP3 inflammasome activation in stimulated microglia and prevent microglia-induced neuronal injury. These results suggest that okanin could be a potential functional food for stroke recovery.

Mi Y et al (2023).

Food Funct.

DOI:

10.1039/d2fo01476a

PubMed:

36511396

Polysaccharides from the seeds of Gleditsia sinensis Lam. attenuate DSS-induced colitis in mice via improving gut barrier homeostasis and alleviating gut microbiota dybiosis.

Qin N et al (2023).

Food Funct.

DOI:

10.1039/d2fo02722d

PubMed:

36510766

Receptor-mediated effects of Δ(9) -tetrahydrocannabinol and cannabidiol on the inflammatory response of alveolar macrophages.

Preteroti MW et al (2023).

Immunol Cell Biol.

DOI:

10.1111/imcb.12614

PubMed:

36510483

Chloroplast gene expression level is negatively correlated with evolutionary rates and selective pressure while positively with codon usage bias in Ophioglossum vulgatum L.

Hao J et al (2022).

BMC Plant Biol.

DOI:

10.1186/s12870-022-03960-8

PubMed:

36510137

Genome-wide identification and functional analysis of the TCP gene family in rye (Secale cereale L.).

Zhan W et al (2023).

Gene.

DOI:

10.1016/j.gene.2022.147104

PubMed:

36509294

The combined analgesic, sedative, and anti-gastric cancer mechanisms of Tinospora sagittata var. yunnanensis (S. Y. Hu) H. S. Lo based on integrated ethnopharmacological data.

Tinospora sagittata var. yunnanensis (TSY) is widely used in traditional medicine for pain relief, but its mechanism and active components are unclear.

Wang QQ et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115990

PubMed:

36509262