Bis(4-glycosyloxybenzyl) 2-isobutyltartrate and dihydrophenanthrene derivatives from the pseudobulbs of Pholidota chinensis and their anti-inflammatory activity.
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- PubMed:
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In this study, researchers investigated the potential benefits of using a traditional plant, Borage, in combination with syrup (BPS) in severe COVID-19 patients in an ICU setting. Borage is a good source of gamma-linolenic acid (GLA). The study aimed to find a possible curative treatment for COVID-19 patients, who still have a high mortality rate globally.
Researchers in Indonesia have identified four compounds from binahong leaves that could interact with the major protease of the SARS-CoV 2 virus. The compounds - procyanidin, oleic acid, methyl linoleic acid, and vitexin - were tested through molecular dynamics simulation, with procyanidin and vitexin having the best docking scores. While the two compounds showed good performance in interacting with the target protein, they did not conform as well as quercetin, a control ligand. The study may offer new avenues for COVID-19 treatments.