All Studies

Euphorbia tirucalli latex loaded polymer nanoparticles: Synthesis, characterization, in vitro release and in vivo antinociceptive action.

Researchers encapsulated the active substance-containing latex from Euphorbia tirucalli in poly(D,L-lactide-co-glycolide) nanoparticles. These nanoparticles showed good drug encapsulation and release profiles, making them a promising drug delivery device with potential pain-relieving effects.

Rodrigues ML et al (2022).
PLoS One.
PubMed:
36445864

In silico evaluation of flavonoids as potential inhibitors of SARS-CoV-2 main nonstructural proteins (Nsps)-amentoflavone as a multitarget candidate.

Researchers explored the potential of flavonoids as COVID-19 treatment options. Through virtual screening, they identified amentoflavone, found in plants like Ginkgo biloba, as a potential multitarget inhibitor against essential non-structural proteins of the virus. Molecular docking calculations and structural analysis support this potential. Amentoflavone is widely available, low-cost, has no side effects, and a long history of use. Future experiments are needed to validate its effectiveness as an inhibitor against SARS-CoV-2.

Portilla-Martínez A et al (2022).
J Mol Model.
PubMed:
36445575