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Interactive deciphering electron-shuttling characteristics of Coffea arabica leaves and potential bioenergy-steered anti-SARS-CoV-2 RdRp inhibitor via microbial fuel cells.

Researchers explored the antiviral potential of herbal medicine for COVID-19 using microbial fuel cells. Ethanol extracts from air-dried leaves showed the highest bioenergy-stimulating capabilities and exhibited promising antioxidant and anti-inflammatory activities. Molecular docking analysis showed that chlorogenic acid had high binding affinity with RdRp of SARS-CoV-2. These findings suggest that leaves could be a potential medicinal herb for treating COVID-19.

Tsai PW et al (2023).
Ind Crops Prod.
PubMed:
36405420