All Studies

A high-resolution accurate mass approach to identification of graveoline metabolites using ultra-high-performance liquid chromatography combined with a photo diode array detector and quadrupole/time-of-flight tandem mass spectrometry.

Liu H, Guo S and Xi S (2023).
Biomed Chromatogr.
PubMed:
36100977

Phytochemicals of Cocculus hirsutus deciphered SARS-CoV-2 inhibition by targeting main proteases in molecular docking, simulation, and pharmacological analyses.

Researchers aimed to discover natural compounds with anti-COVID-19 properties by testing phytochemicals from a traditional medicine plant against the main proteases of the SARS-CoV-2 virus, which play a key role in replication and transcription. They used computer tools to identify the most promising compounds, and identified betulin, coclaurine, and quinic acid from the plant as showing significant binding affinity to the SARS-CoV-2 main proteases. These compounds could potentially serve as leads for developing specific anti-COVID-19 treatments.

Rajan M et al (2022).
J Biomol Struct Dyn.
PubMed:
36099182