All Studies

Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway.

Liu F et al (2022).
Chin Med.
PubMed:
35922850

Hesperidin hexosomal loaded nanodispersion: insights of its antimycobacterial, cytotoxic and anti-HCoV effects.

Valencia oranges contain hesperidin which has anti-TB and antiviral activity. Hesperidin was isolated and formulated as nanodispersions which showed a MIC of 0.19 µM against TB and significant interactions with the Mycobacterial Dihydrofolate reductase enzyme. The nanodispersions also had a cytotoxic effect against lung cancer at IC=33 µM and significant antiviral activity against Human Coronavirus 229E with IC=258.8 μM. This study suggests that Valencia orange peels could be a source of bioactive metabolites for treating diseases.

Elghani EMA et al (2023).
Nat Prod Res.
PubMed:
35921497

Protective effects of isofraxidin against scopolamine-induced cognitive and memory impairments in mice involve modulation of the BDNF-CREB-ERK signaling pathway.

Isofraxidin is a molecule found in plants that are useful for brain diseases. It is extracted from plants like Sarcandra glabra, Apium graveolens, and Siberian Ginseng.

Lian B et al (2022).
Metab Brain Dis.
PubMed:
35921056

Potential Protective Effects of Ruta Chalepensis L. Extracts Against Gentamicin-Induced Nephrotoxicity via Reduction on Apoptotic, DNA Damage and Oxidative Stress Markers in Mice.

Yıldırım M et al (2022).
Int J Environ Health Res.
PubMed:
35917490