Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway.
- Liu F et al (2022).
- Chin Med.
- PubMed:
- 35922850
Valencia oranges contain hesperidin which has anti-TB and antiviral activity. Hesperidin was isolated and formulated as nanodispersions which showed a MIC of 0.19 µM against TB and significant interactions with the Mycobacterial Dihydrofolate reductase enzyme. The nanodispersions also had a cytotoxic effect against lung cancer at IC=33 µM and significant antiviral activity against Human Coronavirus 229E with IC=258.8 μM. This study suggests that Valencia orange peels could be a source of bioactive metabolites for treating diseases.
Isofraxidin is a molecule found in plants that are useful for brain diseases. It is extracted from plants like Sarcandra glabra, Apium graveolens, and Siberian Ginseng.