5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches.

Study examined the anticancer effects of Rumex obtusifolius (RO) extract and 5-fluorouracil (5-FU) on lung cancer cells. Results show reduced inflammation, increased apoptosis, and potential therapeutic benefits with minimal side effects.

Ginovyan M et al (2024).

Sci Rep.

DOI:

10.1038/s41598-024-65816-5

PubMed:

38918540

Combined Transcriptomics and Metabolomics Analysis Reveals Profenofos-Induced Invisible Injury in Pakchoi (Brassica rapa L.) through Inhibition of Carotenoid Accumulation.

Jia C et al (2024).

J Agric Food Chem.

DOI:

10.1021/acs.jafc.4c03262

PubMed:

38917998

Identification of the function of a key gene NnHCT1 in lignin synthesis in petioles of Nelumbo nucifera.

Zhao S et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.133391

PubMed:

38917921

The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.

Qian YW et al (2024).

Life Sci.

DOI:

10.1016/j.lfs.2024.122862

PubMed:

38917872

Temporal dynamics of chloroplast biogenesis revealed initiation of photosynthesis-related gene expression and protein complexes during alfalfa seed germination.

Ni H et al (2024).

Plant Physiol Biochem.

DOI:

10.1016/j.plaphy.2024.108868

PubMed:

38917738

Screening for promising multi-target bioactive components from Cortex Mori Radicis for the treatment of chronic cor pulmonale based on immobilized beta(1)-adrenergic receptor and beta(2)-adrenergic receptor chromatography.

He Y et al (2024).

J Chromatogr B Analyt Technol Biomed Life Sci.

DOI:

10.1016/j.jchromb.2024.124175

PubMed:

38917653

Relationship of Curcumin with Aging and Alzheimer and Parkinson Disease, the Most Prevalent Age-Related Neurodegenerative Diseases: A Narrative Review.

Curcumin, a bioactive phytochemical found in turmeric, shows promise in combating age-related neurological diseases due to its antioxidant and anti-inflammatory properties. Consuming curcumin may help prevent cognitive decline and memory disorders in the elderly.

Turer BY and Sanlier N (2024).

Nutr Rev.

DOI:

10.1093/nutrit/nuae079

PubMed:

38916925

Effect of apigetrin in pseudo-SARS-CoV-2-induced inflammatory and pulmonary fibrosis in vitro model.

Researchers developed a model of ARDS and PF caused by SARS-CoV-2 in cells. HIF-1α knockdown and apigetrin showed promise in reducing inflammation and fibrosis, suggesting potential for SARS-CoV-2 treatment.

Han H, Kim JE and Lee HJ (2024).

Sci Rep.

DOI:

10.1038/s41598-024-65447-w

PubMed:

38914619