A Novel Chinese Herbal and Corresponding Chemical Formula for Cancer Treatment by Targeting Tumor Maintenance, Progression, and Metastasis.

Song YC, Lee DY and Yeh PY (2022).

Front Pharmacol.

DOI:

10.3389/fphar.2022.907826

PubMed:

35721174

Co-option of a carotenoid cleavage dioxygenase gene (CCD4a) into the floral symmetry gene regulatory network contributes to the polymorphic floral shape-color combinations in Chrysanthemum sensu lato.

Zhang CJ et al (2022).

New Phytol.

DOI:

10.1111/nph.18325

PubMed:

35719106

[Distribution and bioactivity of polyphenols in Opuntia ficus-indica (L. ) Mill].

Zhou M et al (2022).

Wei Sheng Yan Jiu.

DOI:

10.19813/j.cnki.weishengyanjiu.2022.03.020

PubMed:

35718912

In vitro study on efficacy of PHELA, an African traditional drug against SARS-CoV-2.

Researchers investigated an herbal combination of four African medicinal plants known as PHELA as a potential therapy for COVID-19. In vitro testing found that PHELA inhibited > 90% of SARS-CoV-2 and SARS-CoV infection as well as close to 100% of MERS-CoV infection. In silico docking studies showed strong binding energy interactions between compounds in PHELA and SARS-CoV-2 proteins. PHELA has potential as a COVID-19 therapeutic.

Matsabisa MG et al (2022).

Sci Rep.

DOI:

10.1038/s41598-022-13599-y

PubMed:

35718800

[Lignans from Agrimonia pilosa].

Jia ZL et al (2022).

Zhongguo Zhong Yao Za Zhi.

DOI:

10.19540/j.cnki.cjcmm.20220301.201

PubMed:

35718520

Stellerasespenes A‒E: Sesquiterpenoids from Stellera chamaejasme and their anti-neuroinflammatory effects.

Researchers have isolated nine sesquiterpenoids from Stellera chamaejasme roots, five of which are previously undescribed. These were tested for their ability to inhibit NO production in BV2 cells induced by LPS. Stellerasespene A was found to have higher inhibitory activity than minocycline, a positive control, indicating its potential use as an anti-inflammatory agent.

Cheng ZY et al (2022).

Phytochemistry.

DOI:

10.1016/j.phytochem.2022.113275

PubMed:

35718134

Deciphering key regulators of Inonotus hispidus petroleum ether extract involved in anti-tumor through whole transcriptome and proteome analysis in H22 tumor-bearing mice model.

Li Z and Bao H (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115468

PubMed:

35718054

Loquat (Eriobotrya japonica (Thunb) Lindl.): Evaluation of nutritional value, polyphenol composition, antidiabetic effect, and toxicity of leaf aqueous extract.

Khouya T et al (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115473

PubMed:

35718052