Antiepileptic Therapy of Abrus cantoniensis: Evidence from Network Pharmacology.
Researchers used network pharmacology to explore the mechanism behind Abrus cantoniensis, an herb used for antiepileptic treatment. Through various databases, they found three active components mainly related to -sitosterol and stigmasterol, 92 intersection targets of epilepsy including 9 core targets, and 8 core targets as flavanone constituent proteins. Additionally, they found that Abrus cantoniensis is mainly connected to epilepsy through the neuroactive ligand-receptor interaction signaling pathway, the neurodegeneration pathway, and multiple disease signaling pathway. The study provides a new strategy for antiepileptic treatment using Abrus cantoniensis.
- Wang Y et al (2022).
- Evid Based Complement Alternat Med.
- DOI:
- 10.1155/2022/7748787
- PubMed:
- 35707480