In Vitro and In Silico Evaluation of ACE2 and LOX Inhibitory Activity of Origanum Essential Oils and Carvacrol.
In this study, researchers evaluated the inhibitory potentials of commercial essential oils and their main component, carvacrol. The essential oils, including and , were found to inhibit angiotensin-converting enzyme 2 and lipoxygenase enzymes. Carvacrol showed the highest inhibitory activity for both enzymes. The findings suggest that these essential oils and carvacrol have potential health benefits, particularly in regulating blood pressure and inflammation. Further studies are needed to ensure their safety and effectiveness.
- Demirci F et al (2023).
- Planta Med.
- DOI:
- 10.1055/a-1828-2479
- PubMed:
- 35439836