All Studies

In Vitro and In Silico Evaluation of ACE2 and LOX Inhibitory Activity of Origanum Essential Oils and Carvacrol.

In this study, researchers evaluated the inhibitory potentials of commercial essential oils and their main component, carvacrol. The essential oils, including and , were found to inhibit angiotensin-converting enzyme 2 and lipoxygenase enzymes. Carvacrol showed the highest inhibitory activity for both enzymes. The findings suggest that these essential oils and carvacrol have potential health benefits, particularly in regulating blood pressure and inflammation. Further studies are needed to ensure their safety and effectiveness.

Demirci F et al (2023).
Planta Med.
PubMed:
35439836

Anti-COVID-19 potential of Azadirachta indica (Neem) leaf extract.

COVID-19 can cause multiple organ distress syndrome (MODS) and has high mortality rates in severe cases, especially in those with comorbidities like cardiovascular disease and diabetes. The involvement of the vascular endothelium (VE) is a plausible explanation for MODS, as the VE connects all target organs and systems. This study hypothesizes that the acetone-water extract of Neem plant leaves, which has been shown to prevent the binding of other pathogens to the VE, could prevent SARS-CoV-2 binding and therefore be an effective treatment for COVID-19. The extract is readily available, simple to prepare, and non-toxic, making it a promising therapeutic option. Clinical trials are needed to investigate its efficacy further.

Eze MO et al (2022).
Sci Afr.
PubMed:
35434432

UHPLC-ESI-QTOF-MS(2) analysis of Acacia pennata extract and its effects on glycemic indices, lipid profile, pancreatic and hepatorenal alterations in nicotinamide/streptozotocin-induced diabetic rats.

Shao H et al (2022).
Food Sci Nutr.
PubMed:
35432973