Photodermatitis and ocular changes in nine horses after ingestion of wild parsnip (pastinaca sativa).
- Winter JC et al (2022).
- BMC Vet Res.
- PubMed:
- 35219345
Researchers investigated the antidepressant and anxiolytic properties of a certain plant called HLDS, which is traditionally used to manage mental health issues. They studied its effects on mice and tried to understand how it works. The findings suggest that HLDS has therapeutic potential for mental health disorders in humans.
Kurarinone, a natural compound, can potentially treat Parkinson's disease (PD) by inhibiting the soluble epoxide hydrolase (sEH) enzyme. In a study, kurarinone alleviated MPTP-induced behavioral deficits, dopaminergic neurotoxicity, and neuroinflammation in mice. Kurarinone's inhibition of sEH was supported by evidence of increased sEH substrates and decreased products, along with inhibition kinetics and cocrystallization. The study suggests that sEH is a promising target for PD treatment and that kurarinone could be a natural candidate for it.