All Studies

Arbutus Unedo Honey and Propolis Ameliorate Acute Kidney Injury, Acute Liver Injury, and Proteinuria via Hypoglycemic and Antioxidant Activity in Streptozotocin-Treated Rats.

Touzani S et al (2022).
Cell Physiol Biochem.
PubMed:
35218633

Datura stramonium abrogates depression- and anxiety-like disorders in mice: possible involvement of monoaminergic pathways in its antidepressant activity.

Researchers investigated the antidepressant and anxiolytic properties of a certain plant called HLDS, which is traditionally used to manage mental health issues. They studied its effects on mice and tried to understand how it works. The findings suggest that HLDS has therapeutic potential for mental health disorders in humans.

Akanji MA et al (2022).
Drug Metab Pers Ther.
PubMed:
35218173

Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model.

Kurarinone, a natural compound, can potentially treat Parkinson's disease (PD) by inhibiting the soluble epoxide hydrolase (sEH) enzyme. In a study, kurarinone alleviated MPTP-induced behavioral deficits, dopaminergic neurotoxicity, and neuroinflammation in mice. Kurarinone's inhibition of sEH was supported by evidence of increased sEH substrates and decreased products, along with inhibition kinetics and cocrystallization. The study suggests that sEH is a promising target for PD treatment and that kurarinone could be a natural candidate for it.

Sun CP et al (2022).
Proc Natl Acad Sci U S A.
PubMed:
35217618