All Studies

Purpurin ameliorated neuropathic allodynia and hyperalgesia by modulating neuronal mitochondrial bioenergetics and redox status in type 1 diabetic mice.

Purpurin, a compound from Rubia tinctorum, relieves neuropathic pain in diabetic mice by enhancing bioenergetics and antioxidant effects. Could lead to improved therapy for diabetic patients with peripheral neuropathy.

Chen W et al (2024).
Eur J Pharmacol.
PubMed:
38897444

Identification of antidepressant constituents from Xiangfu-chuanxiong herbal medicine pair via spectrum-effect relationship analyses, molecular docking and corticosterone-induced PC12 cells.

Study evaluated XF-CX herbal medicine pair ratios for antidepressant effects. XF-CX (2:1) most effective. Identified potential antidepressant constituents. Beneficial for depression treatment mechanism and clinical application.

Li HJ et al (2024).
Fitoterapia.
PubMed:
38897250

Gastrodin prevents myocardial injury in sleep-deprived mice by suppressing ferroptosis through SIRT6.

Gastrodin from orchid plant reduces cardiac injury caused by sleep deprivation by inhibiting ferroptosis through SIRT6 pathway. Important for understanding sleep deprivation effects on heart health.

Wu Y et al (2024).
Naunyn Schmiedebergs Arch Pharmacol.
PubMed:
38896272