Cirsium japonicum var. Maackii Improves Cognitive Impairment under Amyloid Beta(25-35)-Induced Alzheimer's Disease Model.

Researchers studied the protective effects of an herbal medicine called CJM on mice with Alzheimer's disease (AD). They focused on the ethyl acetate fraction from CJM (ECJM), which has anti-inflammatory properties, and found that it improved the mice's spatial and object recognition memory, as well as their learning and memory abilities. The ECJM also inhibited lipid peroxidation and nitric oxide production, indicating that it improves cognitive impairment by reducing oxidative stress. This study suggests that CJM could be used as a treatment for AD and may have potential as a functional food material.

Pang QQ et al (2022).

Biomed Res Int.

DOI:

10.1155/2022/4513998

PubMed:

35036433

Genome-wide identification and characterization of SPX-domain-containing protein gene family in Solanum lycopersicum.

Li C, You Q and Zhao P (2021).

PeerJ.

DOI:

10.7717/peerj.12689

PubMed:

35036163

Genome-wide identification and expression profile of YABBY genes in Averrhoa carambola.

Li C et al (2022).

PeerJ.

DOI:

10.7717/peerj.12558

PubMed:

35036123

Protective effect of isoflavones and triterpenoid saponins from pueraria lobata on liver diseases: A review.

He H et al (2021).

Food Sci Nutr.

DOI:

10.1002/fsn3.2668

PubMed:

35035928

Structure-Based In Silico Investigation of Agonists for Proteins Involved in Breast Cancer.

Roy A et al (2022).

Evid Based Complement Alternat Med.

DOI:

10.1155/2022/7278731

PubMed:

35035508

Dose dependent anticonvulsant activity of Morus nigra in strychnine induced seizures model.

The study evaluated the anti-seizure activity of Morus nigra (black mulberry) in different doses. Groups of rats were given different doses of Morus nigra for 15 days prior to being administered strychnine. Results showed significant seizure protection, particularly in the 500mg/kg dose group, with delayed latency of seizures, decrease in frequency, and decreased duration of jerks. The anticonvulsant activity could be due to potentiation of both Gabaergic and glycinergic activities and the antioxidant activity of Morus nigra could serve as a non-pharmacological treatment for seizure management.

Zehra T, Sarfaraz S and Ikram R (2021).

Pak J Pharm Sci.

PubMed:

35034877

Japonicone A and related dimeric sesquiterpene lactones: molecular targets and mechanisms of anticancer activity.

Bailly C and Vergoten G (2022).

Inflamm Res.

DOI:

10.1007/s00011-021-01538-y

PubMed:

35034149

Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis.

Jang SA et al (2022).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2022.112640

PubMed:

35033946