DNA Barcoding of Two Thymelaeaceae Species: Daphne mucronata Royle and Thymelaea hirsuta (L.) Endl.
- Alkaraki AK et al (2021).
- Plants (Basel).
- PubMed:
- 34686008
New SARS-CoV-2 variants of concern have multiple mutations in the ACE2 receptor recognition site, potentially causing immune escape. Researchers found that common dandelion can block the virus spike protein's interaction with the ACE2 receptor in kidney and lung cells, including mutant forms. High-molecular-weight compounds in the water-based extract account for this effect. The extract also prevented infection and pro-inflammatory response in lung cells using both the original virus and a new variant. This safe medicinal plant could be further researched as a non-invasive, oral post-exposure prophylaxis for SARS-CoV-2.