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Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for 'Alzheimer's disease: an in silico approach.

This study explored the potential of certain plant compounds found in tomatoes to treat Alzheimer's disease by inhibiting cholinesterases. Researchers used software to analyze four potential inhibitors and found that neoxanthin was the safest and most effective at binding to the cholinesterases. It also remained stable in a simulated biological environment, indicating it could be a viable drug candidate for treating Alzheimer's. These findings highlight the potential therapeutic properties of phytochemicals in tomatoes for combating Alzheimer's disease.

Bakare OO et al (2021).
BMC Mol Cell Biol.
PubMed:
34592924