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A study investigated the neuroprotective effect of wild lowbush blueberry on rats with induced cerebral ischemia and reperfusion. The rats were injected with BBE for 14 days and several parameters were measured. Results showed that BBE significantly decreased oxidative stress levels and increased antioxidant power levels in the hippocampus and serum, while also modulating neuroinflammatory cascades and protecting neurons against ischemic death. The study suggests that BBE may have potent neuroprotective efficacy against cerebral ischemia and reperfusion.