Reshaping the root endophytic microbiota in plants to combat mercury-induced stress.

Feng T et al (2024).

Sci Total Environ.

DOI:

10.1016/j.scitotenv.2024.174019

PubMed:

38885713

Gastrodin relieves Parkinson's disease-related motor deficits by facilitating the MEK-dependent VMAT2 to maintain dopamine homeostasis.

Researchers found that dysregulation of VMAT2 leads to DA neurotoxicity and motor deficits in Parkinson's disease, but treatment with GTD derived from Gastrodia elata Blume may help regulate this dysfunction. This suggests GTD could be a potential treatment for PD.

Zhao M et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155819

PubMed:

38885579

Exploring the mechanism of Scleromitrion diffusum (Willd.) in treating lung cancer based on network pharmacology and experimental validation.

SDW components target 88 genes in lung cancer treatment, inhibiting cell proliferation via P I3K/Akt and MEK/ERK pathways. SDW may regulate apoptosis and proliferation in lung cancer therapy. Valuable insights into molecular mechanisms provided through network pharmacology, molecular docking, and experimental validation.

Huang S et al (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2367244

PubMed:

38885333

Anthelmintic effects of some medicinal plants on different life stages of Fasciola hepatica: Evidence on oxidative stress biomarkers, and DNA damage.

Allahyari M, Malekifard F and Yakhchali M (2024).

PLoS Negl Trop Dis.

DOI:

10.1371/journal.pntd.0012251

PubMed:

38885188

Antifungal activity and possible mechanism of Streptomyces nojiriensis 9-13 against Mycogone sp., causing wet bubble disease on Agaricus bisporus.

Strain 9-13, identified as Streptomyces nojiriensis, shows strong inhibitory activity against Mycogone species causing Wet Bubble Disease in Agaricus bisporus. Extracts destroy fungal cells, reducing disease severity by up to 87.32%. Potential biocontrol agent for mushroom production.

Shi N et al (2024).

Plant Dis.

DOI:

10.1094/PDIS-03-24-0645-RE

PubMed:

38885024

In silico and in vitro studies for the identification of small molecular inhibitors from Euphorbia hirta Linn for rheumatoid arthritis: targeting TNF-α-mediated inflammation.

Velmurugan Y et al (2024).

Mol Divers.

DOI:

10.1007/s11030-024-10900-1

PubMed:

38884873

A structural variation in the promoter of the leucoanthocyanidin reductase gene AaLAR1 enhances freezing tolerance by modulating proanthocyanidin accumulation in kiwifruit (Actinidia arguta).

Sun S et al (2024).

Plant Cell Environ.

DOI:

10.1111/pce.15003

PubMed:

38884345

Effect of postharvest grape dehydration on chemical composition, antioxidant activity and sensory characeteristics of Marselan wines.

Xi C et al (2024).

Food Chem X.

DOI:

10.1016/j.fochx.2024.101503

PubMed:

38883920