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The Effect of Ferula communis Extract in Escherichia coli Lipopolysaccharide-Induced Neuroinflammation in Cultured Neurons and Oligodendrocytes.

Ferutinin, a compound found in the plant genus L., has properties that may benefit the treatment of neurodegenerative and demyelinating diseases. In an experimental system, human neurons and oligodendrocytes were treated with a pro-inflammatory agent and then pretreated with ferutinin. Results suggested that ferutinin may act as an antioxidant and anti-inflammatory agent. However, further studies are needed to confirm its potential use as a treatment strategy for diseases characterized by inflammation and oxidative stress.

Maiuolo J et al (2021).
Int J Mol Sci.
PubMed:
34360675