Polygonatum sibiricum Polysaccharides Alleviate Depressive-like Symptoms in Chronic Restraint Stress-Induced Mice via Microglial Regulation in Prefrontal Cortex.
PSP, a polysaccharide extracted from natural sources, shows potential as an antidepressant by regulating microglial activity and neuroinflammatory pathways in mice under chronic restraint stress. This study highlights the importance of PSP in treating depression.
- Yuan ZY et al (2024).
- Polymers (Basel).
- PubMed:
- 39204578