All Studies

Insight into potent leads for alzheimer's disease by using several artificial intelligence algorithms.

This study used a network pharmacology-based approach to investigate potential Traditional Chinese Medicine candidates as treatment targets for Alzheimer's disease (AD). Artificial Intelligence algorithms were employed to predict the bioactivity of the candidates and to explore the predicted results efficiently. The study showed that herbs Ardisia japonica, Ligusticum chuanxiong, Lippia nodiflora and Mirabilis jalapa might be a potential medicine formula for AD. Binding stability of the potential inhibitors was evaluated using 100 ns of MD simulation. This study elucidates new potential TCM approaches to treat AD.

He X et al (2020).
Biomed Pharmacother.
PubMed:
32559623

Fruit Extract of Pithecellobium dulce (FPD) ameliorates carrageenan-induced acute inflammatory responses via regulating pro-inflammatory mediators.

Dhanisha SS, Drishya S and Guruvayoorappan C (2020).
J Food Biochem.
PubMed:
32557685