All Studies

Antiviral Action of Tryptanthrin Isolated from Strobilanthes cusia Leaf against Human Coronavirus NL63.

Researchers investigated the antiviral properties of the Chinese herbal medicine, (Nees) Kuntze, against the Human coronavirus NL63 (HCoV-NL63), which commonly infects the immunocompromised, children, and elderly. The methanol extract of the plant's leaves and its major components, such as tryptanthrin and indigodole B, effectively inhibited the virus' ability to reproduce and cause cellular damage in infected cells. Tryptanthrin, in particular, prevented various stages of the virus' replication process, including blocking viral RNA genome synthesis and protease activity. The study highlights the potential of the plant extract and its components to combat respiratory viral infections caused by HCoV-NL63.

Tsai YC et al (2020).
Biomolecules.
PubMed:
32120929

Lepidine B from Lepidium sativum Seeds as Multi-Functional Anti- Alzheimer's Disease Agent: In Vitro and In Silico Studies.

In this study, researchers tested the anticholinesterase effects of L. sativum and other plants. They specifically looked at the ability of two compounds, Lepidine B & E, to inhibit various enzymes involved in nervous system signaling. The researchers were able to determine the specific interactions between the compounds and the enzymes. These findings suggest potential therapeutic applications for the compounds in neurological disorders.

Talia S et al (2021).
Curr Comput Aided Drug Des.
PubMed:
32116197

Analgesic and anti-inflammatory properties of hydroalcoholic extracts of Malva sylvestris, Carum carvi or Medicago sativa, and their combination in a rat model.

Seddighfar M, Mirghazanfari SM and Dadpay M (2020).
J Integr Med.
PubMed:
32113847