Isatis tinctoria L. (Woad): A Review of its Botany, Ethnobotanical Uses, Phytochemistry, Biological Activities, and Biotechnological Studies.
- Speranza J et al (2020).
- Plants (Basel).
- PubMed:
- 32121532
Researchers investigated the antiviral properties of the Chinese herbal medicine, (Nees) Kuntze, against the Human coronavirus NL63 (HCoV-NL63), which commonly infects the immunocompromised, children, and elderly. The methanol extract of the plant's leaves and its major components, such as tryptanthrin and indigodole B, effectively inhibited the virus' ability to reproduce and cause cellular damage in infected cells. Tryptanthrin, in particular, prevented various stages of the virus' replication process, including blocking viral RNA genome synthesis and protease activity. The study highlights the potential of the plant extract and its components to combat respiratory viral infections caused by HCoV-NL63.
In this study, researchers tested the anticholinesterase effects of L. sativum and other plants. They specifically looked at the ability of two compounds, Lepidine B & E, to inhibit various enzymes involved in nervous system signaling. The researchers were able to determine the specific interactions between the compounds and the enzymes. These findings suggest potential therapeutic applications for the compounds in neurological disorders.