All Studies

Characterization, quantification of free, esterified and bound phenolics in Kainth (Pyrus pashia Buch.-Ham. Ex D.Don) fruit pulp by UPLC-ESI-HRMS/MS and evaluation of their antioxidant activity.

Prakash O, Baskaran R and Kudachikar VB (2019).
Food Chem.
PubMed:
31326758

Protective Effects of Crude Plant Extracts against Aminochrome-induced toxicity in Human Astrocytoma Cells: Implications for Parkinson's Disease.

The compound aminochrome can cause brain damage and a Parkinson's-like condition. The enzyme GSTM2 in brain cells can protect against aminochrome, but sometimes the protection is not strong enough. Some medicines made from plants may also protect against aminochrome damage.

Ngoungoure VLN et al (2019).
Clin Pharmacol Transl Med.
PubMed:
31321384

Comprehensive Chemical Profiling and Multidirectional Biological Investigation of Two Wild Anthemis Species (Anthemis tinctoria var. Pallida and A. cretica subsp. tenuiloba): Focus on Neuroprotective Effects.

Researchers investigated different extracts of a plant for their antioxidant and enzyme inhibitory effects. All extracts showed antiradical effects, with methanol and aqueous extracts being the best sources of antioxidants. Methanol and ethyl acetate extracts were potent against enzymes that are targets for Alzheimer's disease. The extracts were also studied in an in vitro neurotoxicity paradigm, which showed that the water extract of one of the subspecies of the plant had a neuroprotective effect. The water extract was able to prevent an increase in certain biomarkers associated with brain damage and to restore the activity of certain proteins that are important for neuron function. These findings suggest that extracts from this plant may have a therapeutic role in the treatment of neurodegenerative diseases.

Orlando G et al (2019).
Molecules.
PubMed:
31315236