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Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer's disease by restoring microglial function via a PPAR-γ-dependent mechanism.

Alzheimer's disease (AD) is linked to inflammation, worsened by obesity. Using non-steroidal anti-inflammatory drugs (NSAIDs) can lower the risk of AD, but have side effects. Malva parviflora, a plant with anti-inflammatory properties, is a potential therapeutic option.

Medrano-Jiménez E et al (2019).
J Neuroinflammation.
PubMed:
31291963